Replacement of EVOS Imaging System

General Information Document Type: Presolicitation Synopsis Number: 75N98026Q00793 Posted Date: July 15, 2026 Original Response Date: July 27, 2026 Current Response Date: July 27, 2026 Set Aside: N/A NAICS Code: 334516 Contracting (NIH), (OD) (OLAO) (OALM) Hospital and Laboratory Support Division 6701 Rockledge Drive Bethesda, MD 20817 INTRODUCTION THIS IS A PRE-SOLICITATION NON-COMPETITIVE (NOTICE OF INTENT) SYNOPSIS TO AWARD A CONTRACT OR PURCHASE ORDER WITHOUT PROVIDING FOR FULL OR OPEN COMPETITION (INCLUDING BRAND-NAME). The National Institutes of Health (NIH) intends to negotiate and award a contract without providing for full and open competition (Including brand-name) to: Life Technologies Corporation 5781 Van Allen Way Carlsbad, CA 92008 NORTH AMERICAN INDUSTRY SYSTEM (NAICS) CODE The intended procurement is classified under NAICS code 334516 with a Size Standard $1000. REGULATORY AUTHORITY The resultant contract will include all applicable provisions and clauses in effect through the Federal Acquisition Circular (FAC) 2026-01, March 13, 2026. This acquisition is conducted under the procedures as prescribed in FAR subpart 13-Simplified Acquisition Procedures at an amount not exceeding the simplified acquisition threshold ($350,000). STATUTORY AUTHORITY This acquisition is conducted under the authority of the Federal Acquisition Regulation (FAR) Part 13-Simplified Acquisition Procedures, Subpart 13.106-1 (b) (1), Soliciting from a single source and is not expected to exceed the simplified acquisition threshold. Contracts awarded using FAR Part 13-Simplified Acquisition Procedures are exempt from the

requirements of FAR Part 6-Competition

Requirements. GENERAL INFORMATION Title: Replacement of EVOS imaging system

Background Information: The EVOS imaging system is a critical instrument supporting research conducted by the Mili lab as well as additional groups within the Laboratory of Cellular and Molecular Biology (LCMB), NIH/NCI. The system has served as a workhorse instrument for visualizing live and fixed cell populations—a fundamental requirement for experimental studies of cancer cells expressing fluorescently-labeled pro-teins or treated with fluorescent compounds. Routine monitoring of these cell lines requires a dedicated microscope system for daily assessment of cell growth and maintenance of optimal culture conditions. Furthermore, prior to initiating costly and time-intensive experimental protocols, expression patterns and levels of fluorescent constructs must be evaluated to ensure the acquisition of high-quality, repro-ducible data. The system additionally provides critical imaging capabilities, including high-quality sin-gle time-point and time-lapse acquisitions across multiple fluorescence channels. It thus serves as a valuable alternative for applications that do not require the high-resolution capabilities of higher-end confocal microscopes, thereby reducing demand on these heavily-utilized resources. The existing EVOS system was acquired over 12 years ago and after such a long time of continuous use, it is nearing end-of-life and experiencing reliability issues. Prompt replacement is essential to pre-vent significant disruption to the active intramural research programs this instrument supports, and to protect the scientific productivity and mission continuity of LCMB labs.. CLOSING STATEMENT This synopsis is not a request for competitive proposals. However, interested parties may identify their interest and capability to respond to this notice. Responses to this notice shall contain sufficient information to establish the interested parties' bona-fide capabilities for fulfilling the requirement and include a technical proposal, a cost-price proposal, the

period of performance, the Unique Entity ID (UEI), the Taxpayer Identification Number (TIN), and the certification of business size. All offerors must have an active registration in the System for Award Management (SAM) www.sam.gov. A determination by the Government not to compete this proposed contract based upon responses to this notice is solely within the discretion of the Government. The information received will normally be considered solely for the purposes of determining whether to proceed on a non-competitive basis or to conduct a competitive procurement. All responses must be received by July 27, 2026 at 9:00 AM Eastern time and must reference solicitation number 75N98026Q00793. Responses may be submitted electronically to Mr. James Law,

Contracting Officer at [email protected]. Fax responses will not be accepted. "All responsible sources may submit a capability statement, proposal, or quotation, which shall be considered by the agency.” LAW, JAMES B Contracting ., SUITE 503L (No Street Address