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Neuropathology Characterization for Brain Atlas Project

Health & Human Services (HHS) > National Institute On Aging > Center for Alzheimer’s Disease and Related DementiasSol: 75N98026Q00313
SBFFP
$10K – $123K per task order

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Quick Brief

The National Institutes of Health, through the National Institute on Aging, is procuring neuropathology characterization services to support the Brain Atlas Project, which aims to map brain cell types and gene activity differences between healthy and Alzheimer’s-affected brains to identify therapeutic targets. The work requires precise sample processing, digital imaging, data platform compliance, and timely deliverables under a Lowest Price Technically Acceptable evaluation model.

Generated 29d ago

Scope & Requirements

Neuropathology services to analyze brain tissue samples for gene expression and cellular changes associated with Alzheimer’s disease, supporting the creation of a human brain atlas to identify disease-related cell types and therapeutic targets.

Deliverables

  • Neuropathology analysis of brain tissue samples
  • Digital imaging data of cellular structures
  • Processed gene activity data aligned with brain regions
  • Compliant data platform outputs for research use

Evaluation Criteria

  1. Technical Acceptability (Pass/Fail)
  2. Required Sample Processing Capabilities
  3. Digital Imaging & Data Platform Requirements
  4. Schedule & Turnaround
  5. Deliverables Compliance
  6. Staffing & Key Personnel
  7. Facilities and Equipment
  8. Price

Contract Details

Contract Typei
FFP
Contract Value
$10K – $123K per task order
IDIQ ceiling: $41.5M
Similar contracts award $10K$123K (median $32K, 7,005 awards)
Not expected to exceed the simplified acquisition threshold
Period of Performance
2026-06-01 to 2027-05-30
NAICS Codes
Place of Performance
Bethesda, MD, US
Set-Asides
SB

Qualifications & Eligibility

Set-Aside Category
Small Business
NAICS Size Standard
$41.5 million
Required Registrations
  • SAM.gov

Agency & Contact

Contracting Organization

Agency
HEALTH AND HUMAN SERVICES, DEPARTMENT OF
Sub-Agency
National Institute on Aging
Office
Center for Alzheimer’s Disease and Related Dementias

Point of Contact

John A. Smith
Contracting Officer
(202) 555-0100

Key Dates

Published1mo ago
May 5, 2026
Became Solicitation29d ago
May 5, 2026
Tracked
Last Updated28d ago
May 7, 2026
Response Due14d ago
May 20, 2026
Period of Performance Start3d ago
Jun 1, 2026
Period of Performance Endin 12mo
May 30, 2027

Description

(COMPETITIVE) Title: Neuropathology characterization for the Brain Atlas Project

  • (i) This is a combined for commercial items prepared in accordance with FAR Subpart 12.6, as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; proposals are being requested, and a separate written solicitation will not be issued.
  • (ii) The solicitation number is 75N98026Q00313. This solicitation is issued as a competitive combined for commercial products or commercial services. The Government intends to award a contract or purchase order resulting from this solicitation using full and open competition. This acquisition is conducted under the authority of FAR 12.603, Streamlined Solicitation for Commercial Products or Commercial Services, and is not expected to exceed the simplified acquisition threshold. The National Institutes of Health (NIH), , seeks to award a firm fixed price purchase order to the responsible offeror whose proposal represents the best value to the Government.
  • (iii) The solicitation document and incorporated provisions and clauses are those in effect through Federal Acquisition Circular (2026-01).
  • (iv) The associated NAICS code is 621511, and the small business size standard is $41.5 million. This requirement is set aside for small business
  • (v) Description of Requirement: The National Institute on Aging (NIA) requires neuropathology services support of the Brain Atlas project which was established in 2022. NIA’s Center for Alzheimer’s Disease and Related Dementias is working to better understand the differences between healthy brains and brains affected by Alzheimer’s disease at the cellular level. Researchers are working to create a human brain atlas or map of different brain cell types based on their gene activity. Researchers can use this atlas to investigate cell types present in brain regions affected in disease. Many different cells in a diseased brain experience change in their gene expression and downstream intracellular activities. The neuropathology analysis will lead to a better understanding of Alzheimer’s Disease and the prioritization of potential target genes, pathways, and future therapeutics. Please refer to the Statement of Work (SOW) for additional information.
  • (vi) Delivery Location: NIH/NIA 9000 Rockville Pike RM 170 Bethesda, MD 20892 USA
  • (vii)

Period of Performance: June 01, 2026 to May 30, 2027 (viii) The provision at FAR 52.212-1,

Instructions to Offerors—Commercial Items, applies to this acquisition. Add any agency-specific instructions as required.

  • (ix) The provision at FAR 52.212-2, Evaluation—Commercial Items, applies to this acquisition.
  • (a) The Government will award a contract resulting from this solicitation to the responsible offeror whose offer conforming to the solicitation represents the best value to the Government, price and other factors considered.
  • (b) Evaluation Factors: Technical Acceptability (Pass/Fail) Required Sample Processing Capabilities Digital Imaging & Data Platform

Requirements Schedule & Turnaround

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