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The Department of Health and Human Services is procuring innovative solutions under the Technology Integrator and Accelerator (TIGAR) initiative to enhance the storage and distribution of complex biologics. Key requirements include the development of technologies that enable temperature-flexible storage and improve shelf-life stability without introducing high costs or complexity. Proposals should focus on overcoming current limitations in biological systems and ensuring safe storage in various environmental conditions.
The TIGAR initiative aims to develop technologies for stabilizing regenerative tissues and organs, focusing on temperature-flexible storage solutions for complex biologics.
The ISO was updated to extend the Solution Video submission deadline to August 12, 2026 and the Full Proposal submission deadline to September 17, 2026 for intake Group 1.
See page 3 of the full text ISO for more information.
Amendment 3 (1) Appendix B was updated to remove track changes (2) Appendix C4 was updated to remove an erroneous comment.
Amendment 2 (1) Instructions on how to submit a Solution Video were added to the ISO (see pages 7-8). (2) Information related to the Video Captions file was added to Appendix B.0 (Solution Video Format and Instructions). (3) The instructions in Appendix B.1 (Template for Supplemental Slides) were simplified, and a Cost Summary slide was added (see Slide 7). (4) Appendix C.3 was updated to reference "Phase" rather than "Year" for clarity. (5) The Administation and National Policy document in Appendix C.4 was replaced with an updated document.
Amendment 1 The ISO was updated with the new webinar and webinar registration dates.
Effort Description: TIGAR Exploratory Topic will forge entirely new paths to stabilizing regenerative tissues and organs by seeding the development of enabling technologies that can unlock temperature-flexible storage in increasingly larger and more complex biological systems.
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