Cell Sorter for Diabetes Molecular Genetics Section
The Department of Health and Human Services is procuring a BD FACSMelody cell sorter for the Diabetes Molecular Genetics Section at the National Institute of Diabetes and Digestive and Kidney Diseases. This equipment will enable researchers to analyze and isolate specific cell populations from stem cell-derived pancreatic islet organoids, enhancing their ability to conduct experiments focused on cell identity and maturation while reducing reliance on costly single-cell sequencing methods.
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Contract Details
- Estimated Value
- est. $14K – $88KSimilar contracts award $14K to $89K (median $33K, 26,951 awards)Within typical range
- NAICS Codes
- Place of Performance
- Bethesda, MD, USA
Agency & Contact
Contracting Organization
- Agency
- HEALTH AND HUMAN SERVICES, DEPARTMENT OF
Point of Contact
Key Dates
Description
MANY EXPERIMENTS REQUIRE ISOLATION AND ANALYSIS OF SPECIFIC CELL POPULATIONS BECAUSE MIXED CELL POPULATIONS CAN PRODUCE UNCLEAR OR MISLEADING RESULTS. ALTHOUGH SINGLE-CELL SEQUENCING CAN IDENTIFY INDIVIDUAL CELL TYPES, IT IS COSTLY AND NOT PRACTICAL FOR ROUTING USES. AMORE EFFICIENT APPROACH IS TO SEPARATE CELLS BASED ON PROTEINS EXPRESSED ON THE CELL SURFACE. THE BD FACSMELODY CELL SORTGER WITH THREE LASERS AND NINE-COLOR CAPABILITY WILL ALLOW RESEARCHERS TO ANALYZE AND ISOLATE SPECIFIC CELL POPULATIONS FROM ORGANOIDS USING FLUORESCENT MARKERS. THIS CAPABILITY WITH SUPPORT DOWNSTREAM EXPERIMENTS FOCUSED ON CELL IDENTITY, MATURATION, AND RESPOSE TO EXPERIMENTAL CONDITIONS WHILE REDUCING RELIANCE ON MORE EXPENSIVE SINGLE-CELL SEQUENCING METHODS Vishnuvajjala Hanumanth Rao Contracting ., SUITE 503L (No Street Address
2) BETHESDA, MD 20892 USA to this opportunity.
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