Large-Scale High-Density Array-Based Genotyping Analysis Services

The US Army Army Research Institute of Environmental Medicine (USARIEM) requires requires assessing the genome of soldiers who volunteer for research studies. The Military Nutrition Division requires a vendor capable of delivering large-scale, high-density array-based genotyping services for 648 DNA samples collected as part of the Military Health and Nutrition Examination Survey (MHANES). Genomics analysis (i.e., targeted measurement of millions of Single Nucleotide Polymorphisms [SNPs] in the genome and assessment of specific SNPs) is required to support analyses in ongoing research studies. Genomic analysis of DNA using array-based genotyping enables targeted and reproducible measurement of hundreds of thousands to millions of known human variants and facilitates high-resolution imputation to tens of millions of additional variants. For this project, the Illumina Global Diversity Array (GDA), which includes approximately 1.8 million genome-wide markers, is required to support population genetic analyses, ancestry inference, polygenic score calculation, and genome-wide association studies (GWAS). Nicholas VanDevander Alternative

Point of Contact Erin Maddox Contracting & D CONTRACTING DIVISION 1 808 SCHREIDER STREET FORT DETRICK, MD 21702 USA to this opportunity. Attachment 2 - QASP Genomics Analyses.docx Attachment 1 - Performance Work Statement .docx